Allo-antibody production after intraarticular administration of mesenchymal stem cells (MSCs) in an equine osteoarthritis model: effect of repeated administration, MSC inflammatory stimulation, and equine leukocyte antigen (ELA) compatibility

BACKGROUND: Antibody production after allogeneic administration of mesenchymal stem cells (MSCs) could impact their clinical application. Proinflammatory priming of MSCs can potentiate their regulatory ability in vivo but increased expression of major histocompatibility complex (MHC) might augment t...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Barrachina, Laura, Cequier, Alina, Romero, Antonio, Vitoria, Arantza, Zaragoza, Pilar, Vázquez, Francisco José, Rodellar, Clementina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006079/
https://ncbi.nlm.nih.gov/pubmed/32028995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-1571-8
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