ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and claudin-1 through a ZEB1-Dependent Transcriptional Mechanism

PURPOSE: ZIP4 is overexpressed in human pancreatic cancer and promotes tumor growth. However, little is known about the role of ZIP4 in advanced stages of this dismal neoplasm. Our goal is to study the underlying mechanism and define a novel signaling pathway controlled by ZIP4 modulating pancreatic...

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Publicado no:Clin Cancer Res
Main Authors: Liu, Mingyang, Yang, Jingxuan, Zhang, Yuqing, Zhou, Zhijun, Cui, Xiaobo, Zhang, Liyang, Fung, Kar-Ming, Zheng, Wei, Allard, Felicia D., Yee, Eric U., Ding, Kai, Wu, Huanwen, Liang, Zhiyong, Zheng, Lei, Fernandez-Zapico, Martin E., Li, Yi-Ping, Bronze, Michael S., Morris, Katherine T., Postier, Russell G., Houchen, Courtney W., Yang, Jing, Li, Min
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006048/
https://ncbi.nlm.nih.gov/pubmed/29615456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0263
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