CD229 CAR T cells eliminate multiple myeloma and tumor propagating cells without fratricide

Multiple myeloma (MM) is a plasma cell malignancy and most patients eventually succumb to the disease. Chimeric antigen receptor (CAR) T cells targeting B-Cell Maturation Antigen (BCMA) on MM cells have shown high-response rates, but limited durability. CD229/LY9 is a cell surface receptor present o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Radhakrishnan, Sabarinath V., Luetkens, Tim, Scherer, Sandra D., Davis, Patricia, Vander Mause, Erica R., Olson, Michael L., Yousef, Sara, Panse, Jens, Abdiche, Yasmina, Li, K. David, Miles, Rodney R., Matsui, William, Welm, Alana L., Atanackovic, Djordje
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005855/
https://ncbi.nlm.nih.gov/pubmed/32034142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14619-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados