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Effect of immediate cold formalin fixation on phosphoprotein IHC tumor biomarker signal in liver tumors using a cold transport device

Phosphoproteins are the key indicators of signaling network pathway activation. Many disease treatment therapies are designed to inhibit these pathways and effective diagnostics are required to evaluate the efficacy of these treatments. Phosphoprotein IHC have been impractical for diagnostics due to...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lerch, Melissa L., Kenerson, Heidi L., Chafin, David, Westerhoff, Maria, Theiss, Abbey, Otter, Michael, Yeung, Raymond S., Baird, Geoffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005752/
https://ncbi.nlm.nih.gov/pubmed/32034185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58257-3
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