A blocking monoclonal antibody to CCL24 alleviates liver fibrosis and inflammation in experimental models of liver damage

BACKGROUND & AIMS: C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). The aim of the study was to evaluate the involvement of the CCL24-CCR3 axis in liver fibrosis and inflammation an...

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Detalhes bibliográficos
Publicado no:JHEP Rep
Main Authors: Segal-Salto, Michal, Barashi, Neta, Katav, Avi, Edelshtein, Vicktoria, Aharon, Arnon, Hashmueli, Sharon, George, Jacob, Maor, Yaakov, Pinzani, Massimo, Haberman, Dan, Hall, Andrew, Friedman, Scott, Mor, Adi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005554/
https://ncbi.nlm.nih.gov/pubmed/32039405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2019.100064
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