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Automated high-throughput heartbeat quantification in medaka and zebrafish embryos under physiological conditions

Accurate quantification of heartbeats in fish models is an important readout to study cardiovascular biology, disease states and pharmacology. However, dependence on anaesthesia, laborious sample orientation or requirement for fluorescent reporters have hampered the use of high-throughput heartbeat...

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Publicat a:Sci Rep
Autors principals: Gierten, Jakob, Pylatiuk, Christian, Hammouda, Omar T., Schock, Christian, Stegmaier, Johannes, Wittbrodt, Joachim, Gehrig, Jochen, Loosli, Felix
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005164/
https://ncbi.nlm.nih.gov/pubmed/32029752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58563-w
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