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A synthetic peptide library for benchmarking crosslinking-mass spectrometry search engines for proteins and protein complexes

Crosslinking-mass spectrometry (XL-MS) serves to identify interaction sites between proteins. Numerous search engines for crosslink identification exist, but lack of ground truth samples containing known crosslinks has precluded their systematic validation. Here we report on XL-MS data arising from...

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Publicat a:Nat Commun
Autors principals: Beveridge, Rebecca, Stadlmann, Johannes, Penninger, Josef M., Mechtler, Karl
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005041/
https://ncbi.nlm.nih.gov/pubmed/32029734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14608-2
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