Molecular profiling of immunoglobulin heavy-chain gene rearrangements unveils new potential prognostic markers for multiple myeloma patients

Multiple myeloma is a heterogeneous disease whose pathogenesis has not been completely elucidated. Although B-cell receptors play a crucial role in myeloma pathogenesis, the impact of clonal immunoglobulin heavy-chain features in the outcome has not been extensively explored. Here we present the cha...

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Detalhes bibliográficos
Publicado no:Blood Cancer J
Main Authors: Medina, Alejandro, Jiménez, Cristina, Sarasquete, M. Eugenia, González, Marcos, Chillón, M. Carmen, Balanzategui, Ana, Prieto-Conde, Isabel, García-Álvarez, María, Puig, Noemí, González-Calle, Verónica, Alcoceba, Miguel, Cuenca, Isabel, Barrio, Santiago, Escalante, Fernando, Gutiérrez, Norma C., Gironella, Mercedes, Hernández, Miguel T., Sureda, Anna, Oriol, Albert, Bladé, Joan, Lahuerta, Juan-José, San Miguel, Jesús F., Mateos, María-Victoria, Martínez-López, Joaquín, Calasanz, María-José, García-Sanz, Ramón
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004993/
https://ncbi.nlm.nih.gov/pubmed/32029700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-020-0283-8
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