Use of Model-Based Compartmental Analysis and a Super-Child Design to Study Whole-Body Retinol Kinetics and Vitamin A Total Body Stores in Children from 3 Lower-Income Countries

BACKGROUND: Model-based compartmental analysis has been used to describe and quantify whole-body vitamin A metabolism and estimate total body stores (TBS) in animals and humans. OBJECTIVES: We applied compartmental modeling and a super-child design to estimate retinol kinetic parameters and TBS for...

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Bibliographic Details
Published in:J Nutr
Main Authors: Ford, Jennifer Lynn, Green, Joanne Balmer, Haskell, Marjorie J, Ahmad, Shaikh M, Mazariegos Cordero, Dora Inés, Oxley, Anthony, Engle-Stone, Reina, Lietz, Georg, Green, Michael H
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Methodology and Mathematical Modeling
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004890/
https://ncbi.nlm.nih.gov/pubmed/31535129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jn/nxz225
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