Effect of levetiracetam on time to high-dose methotrexate clearance in patients with hematologic malignancies

High-dose methotrexate (HDMTX) is a commonly used treatment for hematologic malignancies involving the central nervous system (CNS). Two case reports described possible delayed methotrexate clearance in patients receiving concurrent levetiracetam while a retrospective cohort study did not find this...

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Udgivet i:J Clin Pharmacol
Main Authors: Lou, Uvette, Kwok, Jamie, Nguyen, Thu Anne, Zhou, Allen, Luk, Samantha O.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004859/
https://ncbi.nlm.nih.gov/pubmed/31729053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1544
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