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Multi-center, randomized, double-blind, placebo-controlled, exploratory study to evaluate the efficacy and safety of HAD-B1 for dose-finding in EGFR positive and locally advanced or metastatic NSCLC subjects who need Afatinib therapy: Study protocol clinical trial (SPIRIT Compliant)

BACKGROUND: In recent studies, afatinib, a second-generation inhibitor, showed superior outcomes, when compared to the first-generation of EGFR-tyrosine kinase inhibitors (TKIs), such as erlotinib and gefitinib, in patients with advanced non-small cell lung cancer (NSCLC) harboring mutations of epid...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Medicine (Baltimore)
Egile Nagusiak: Park, So-Jung, Kang, Hwi-Joong, Jun, Hyung-Joon, Shin, Seong-Hoon, Yoo, Hwa-Seung
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Wolters Kluwer Health 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004641/
https://ncbi.nlm.nih.gov/pubmed/31977865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000018735
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