Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly

Retrovirus assembly is driven by the multidomain structural protein Gag. Interactions between the capsid domains (CA) of Gag result in Gag multimerization, leading to an immature virus particle that is formed by a protein lattice based on dimeric, trimeric, and hexameric protein contacts. Among retr...

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Pubblicato in:PLoS Pathog
Autori principali: Dick, Robert A., Xu, Chaoyi, Morado, Dustin R., Kravchuk, Vladyslav, Ricana, Clifton L., Lyddon, Terri D., Broad, Arianna M., Feathers, J. Ryan, Johnson, Marc C., Vogt, Volker M., Perilla, Juan R., Briggs, John A. G., Schur, Florian K. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004409/
https://ncbi.nlm.nih.gov/pubmed/31986188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008277
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