Discovery, expression, cellular localization, and molecular properties of a novel, alternative spliced HP1γ isoform, lacking the chromoshadow domain

By reading the H3K9Me3 mark through their N-terminal chromodomain (CD), HP1 proteins play a significant role in cancer-associated processes, including cell proliferation, differentiation, chromosomal stability, and DNA repair. Here, we used a combination of bioinformatics-based methodologies, as wel...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mathison, Angela, Milech De Assuncao, Thiago, Dsouza, Nikita R., Williams, Monique, Zimmermann, Michael T., Urrutia, Raul, Lomberk, Gwen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004349/
https://ncbi.nlm.nih.gov/pubmed/32027651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217452
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