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Lactose drives Enterococcus expansion to promote graft-versus-host disease

Disruption of intestinal microbial communities appears to underlie many human illnesses, but the mechanisms that promote this dysbiosis and its adverse consequences are poorly understood. In patients who received allogeneic hematopoietic cell transplantation (allo-HCT), we describe a high incidence...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Stein-Thoeringer, C.K., Nichols, K.B., Lazrak, A., Docampo, M.D., Slingerland, A.E., Slingerland, J.B., Clurman, A.G., Armijo, G., Gomes, A.L.C., Shono, Y., Staffas, A., Burgos da Silva, M., Devlin, S., Markey, K.A., Bajic, D., Pinedo, R., Tsakmaklis, A., Littmann, E.R., Pastore, A., Taur, Y., Monette, S., Arcila, M.E., Pickard, A.J., Maloy, M., Wright, R.J., Amoretti, L.A., Fontana, E., Pham, D., Jamal, M.A., Weber, D., Sung, A.D., Hashimoto, D., Scheid, C., Xavier, J.B., Messina, J.A., Romero, K., Lew, M., Bush, A., Bohannon, L., Hayasaka, K, Hasegawa, Y., Vehreschild, M.J.G.T., Cross, J.R., Ponce, D.M., Perales, M.A., Giralt, S.A., Jenq, R.R., Teshima, T., Holler, E., Chao, N.J., Pamer, E.G., Peled, J.U., van den Brink, M.R.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003985/
https://ncbi.nlm.nih.gov/pubmed/31780560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aax3760
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