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The fission yeast FHIT homolog affects checkpoint control of proliferation and is regulated by mitochondrial electron transport

Genetic analysis has strongly implicated human FHIT (Fragile Histidine Triad) as a tumor suppressor gene, being mutated in a large proportion of early‐stage cancers. The functions of the FHIT protein have, however, remained elusive. Here, we investigated aph1 (+), the fission yeast homolog of FHIT,...

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Bibliographic Details
Published in:Cell Biol Int
Main Authors: Sjölander, Johanna J., Sunnerhagen, Per
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003880/
https://ncbi.nlm.nih.gov/pubmed/31538680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbin.11241
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