Merkel cell polyomavirus oncoproteins induce microRNAs that suppress multiple autophagy genes

Viruses can inhibit host autophagy through multiple mechanisms, and evasion of autophagy plays an important role in immune suppression and viral oncogenesis. Merkel cell polyomavirus (MCPyV) T‐antigens are expressed and involved in the pathogenesis of a large proportion of Merkel cell carcinoma (MCC...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Kumar, Satendra, Xie, Hong, Shi, Hao, Gao, Jiwei, Juhlin, Carl Christofer, Björnhagen, Viveca, Höög, Anders, Lee, Linkiat, Larsson, Catharina, Lui, Weng‐Onn
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Molecular Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003823/
https://ncbi.nlm.nih.gov/pubmed/31180579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.32503
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