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Phosphoinositide 3-kinase inhibitor AS605240 ameliorates streptozotocin-induced Alzheimer’s disease like sporadic dementia in experimental rats

The quest for chemical entities able to curb the action of the phosphoinositide 3-kinase, (PI3K)/protein kinase B (AKT) signaling pathways is evolving as a potential therapeutic strategy for the treatment and/or prevention of neurodegenerative disorders including Alzheimer's disease (AD). In th...

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Detalhes bibliográficos
Publicado no:EXCLI J
Main Authors: Alluri, Ramesh, Ambati, Sivamallikarjuna Reddy, Routhu, Kasiviswanth, Kopalli, Spandana Rajendra, Koppula, Sushruta
Formato: Artigo
Idioma:Inglês
Publicado em: Leibniz Research Centre for Working Environment and Human Factors 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003642/
https://ncbi.nlm.nih.gov/pubmed/32038117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2019-1997
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