New 1,3-Diynoic Derivatives of Natural Lembehyne B: Stereoselective Synthesis, Anticancer, and Neuritogenic Activity

[Image: see text] An original method has been developed for the synthesis of 1,3-dyine derivatives of natural lembehyne B in high yields (50–67%) and with high selectivity (>98%). The key stage of the synthesis is new Ti-catalyzed cross-cyclomagnesiation of oxygenated and aliphatic 1,2-dienes ind...

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Publicat a:ACS Omega
Autors principals: Dzhemileva, Lilya U., Makarov, Alexey A., Andreev, Evgeny N., Makarova, Elina Kh., Yunusbaeva, Milyausha M., D’yakonov, Vladimir A., Dzhemilev, Usein M.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003515/
https://ncbi.nlm.nih.gov/pubmed/32039334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b03826
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