Mapping the preclinical to clinical evidence and development trajectory of the oncolytic virus talimogene laherparepvec (T-VEC): a systematic review

OBJECTIVE: This study aimed to conduct a systematic review of preclinical and clinical evidence to chart the successful trajectory of talimogene laherparepvec (T-VEC) from the bench to the clinic. DESIGN: This study was a systematic review. The primary outcome of interest was the efficacy of treatme...

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Bibliographische Detailangaben
Veröffentlicht in:BMJ Open
Hauptverfasser: Lalu, Manoj, Leung, Garvin J, Dong, Yuan Yi, Montroy, Joshua, Butler, Claire, Auer, Rebecca C, Fergusson, Dean A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2019
Schlagworte:
Epidemiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003485/
https://ncbi.nlm.nih.gov/pubmed/31796474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2019-029475
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