Paroxetine suppresses reactive microglia-mediated but not lipopolysaccharide-induced inflammatory responses in primary astrocytes

BACKGROUND: Astrocytes are the most abundant glial cells in a brain that mediate inflammatory responses and provide trophic support for neurons. We have previously disclosed that paroxetine, a common selective serotonin reuptake inhibitor, ameliorates LPS-induced microglia activation. However, it re...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Zhang, Xiong, Zhu, Lan-Bing, He, Jia-Hui, Zhang, Hong-Qiu, Ji, Shu-Ya, Zhang, Chao-Nan, Hou, Na-Na, Huang, Chen-Ping, Zhu, Jian-Hong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003432/
https://ncbi.nlm.nih.gov/pubmed/32024542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-1712-0
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