Local delivery of minocycline-loaded PLGA nanoparticles from gelatin-coated neural implants attenuates acute brain tissue responses in mice

BACKGROUND: Neural interfaces often elicit inflammatory responses and neuronal loss in the surrounding tissue which adversely affect the function and longevity of the implanted device. Minocycline, an anti-inflammatory pharmaceutics with neuroprotective properties, may be used for reducing the acute...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Nanobiotechnology
Egile Nagusiak: Holmkvist, Alexander Dontsios, Agorelius, Johan, Forni, Matilde, Nilsson, Ulf J., Linsmeier, Cecilia Eriksson, Schouenborg, Jens
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003334/
https://ncbi.nlm.nih.gov/pubmed/32024534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-0585-9
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