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DNA ADP-Ribosylation Stalls Replication and Is Reversed by RecF-Mediated Homologous Recombination and Nucleotide Excision Repair

ADP-ribosylation of proteins is crucial for fundamental cellular processes. Despite increasing examples of DNA ADP-ribosylation, the impact of this modification on DNA metabolism and cell physiology is unknown. Here, we show that the DarTG toxin-antitoxin system from enteropathogenic Escherichia col...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Rep
Hauptverfasser: Lawarée, Emeline, Jankevicius, Gytis, Cooper, Charles, Ahel, Ivan, Uphoff, Stephan, Tang, Christoph M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003065/
https://ncbi.nlm.nih.gov/pubmed/32023456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.01.014
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