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A new pH sensor localized in the Golgi apparatus of Saccharomyces cerevisiae reveals unexpected roles of Vph1p and Stv1p isoforms

The gradual acidification of the secretory pathway is conserved and extremely important for eukaryotic cells, but until now there was no pH sensor available to monitor the pH of the early Golgi apparatus in Saccharomyces cerevisiae. Therefore, we developed a pHluorin-based sensor for in vivo measure...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Deschamps, Antoine, Colinet, Anne-Sophie, Zimmermannova, Olga, Sychrova, Hana, Morsomme, Pierre
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002768/
https://ncbi.nlm.nih.gov/pubmed/32024908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58795-w
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