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Identification of Key Metabolites in Poly-γ-Glutamic Acid Production by Tuning γ-PGA Synthetase Expression

Poly-γ-glutamic acid (γ-PGA) production is commonly achieved using glycerol, citrate, and L-glutamic acid as substrates. The constitutive expression of the γ-PGA synthetase enabled γ-PGA production with Bacillus subtilis from glucose only. The precursors for γ-PGA synthesis, D- and L-glutamate, are...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Halmschlag, Birthe, Putri, Sastia P., Fukusaki, Eiichiro, Blank, Lars M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002566/
https://ncbi.nlm.nih.gov/pubmed/32083073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00038
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