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RefDNN: a reference drug based neural network for more accurate prediction of anticancer drug resistance

Cancer is one of the most difficult diseases to treat owing to the drug resistance of tumour cells. Recent studies have revealed that drug responses are closely associated with genomic alterations in cancer cells. Numerous state-of-the-art machine learning models have been developed for prediction o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Choi, Jonghwan, Park, Sanghyun, Ahn, Jaegyoon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002431/
https://ncbi.nlm.nih.gov/pubmed/32024872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58821-x
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