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SF3b4: A Versatile Player in Eukaryotic Cells

Spliceosomes are large protein-RNA complexes regulating pre-mRNA processing in eukaryotes. SF3b4 encodes a core subunit of the U2-type spliceosome, loss- or gain-of-function of which often associates with abnormal cell growth, leading to tumorigenesis. Homologs of SF3b4 in other phyla are also essen...

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Publicat a:Front Cell Dev Biol
Autors principals: Xiong, Feng, Li, Sha
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002316/
https://ncbi.nlm.nih.gov/pubmed/32083075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00014
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