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HNF1B-mediated repression of SLUG is suppressed by EZH2 in aggressive prostate cancer

Prostate cancer is the most common malignancy in men in developed countries. Overexpression of enhancer of zeste homolog 2 (EZH2), the major histone H3 lysine 27 methyltransferase, has been connected to prostate cancer malignancy. However, its downstream genes and pathways have not been well establi...

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Vydáno v:Oncogene
Hlavní autoři: Wang, Jianqing, He, Chenxi, Gao, Peng, Wang, Siqing, Lv, Ruitu, Zhou, Huihui, Zhou, Qidong, Zhang, Ke, Sun, Jian, Fan, Caibin, Ding, Guanxiong, Lan, Fei
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002300/
https://ncbi.nlm.nih.gov/pubmed/31636385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-1065-2
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