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Argonautes in extracellular vesicles: artifact or selected cargo?

Argonaute-2 (Ago2) is a key component of the RNA-induced silencing complex (RISC) that mediates downregulation of mRNA by microRNAs. Its presence in extracellular vesicles (EVs) has been postulated to be important for the activity of EV-carried miRNA in modulating gene expression in recipient cells....

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Weaver, Alissa M., Patton, James G.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002258/
https://ncbi.nlm.nih.gov/pubmed/31784424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-2782
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