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Mass drug administrations with dihydroartemisinin-piperaquine and single low dose primaquine to eliminate Plasmodium falciparum have only a transient impact on Plasmodium vivax: Findings from randomised controlled trials

BACKGROUND: Mass administrations of antimalarial drugs (MDA) have reduced the incidence and prevalence of P. falciparum infections in a trial in the Greater Mekong Subregion. Here we assess the impact of the MDA on P. vivax infections. METHODS: Between May 2013 and July 2017, four villages in each M...

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Udgivet i:PLoS One
Main Authors: Phommasone, Koukeo, van Leth, Frank, Peto, Thomas J., Landier, Jordi, Nguyen, Thuy-Nhien, Tripura, Rupam, Pongvongsa, Tiengkham, Lwin, Khin Maung, Kajeechiwa, Ladda, Thwin, May Myo, Parker, Daniel M., Wiladphaingern, Jacher, Nosten, Suphak, Proux, Stephane, Nguon, Chea, Davoeung, Chan, Rekol, Huy, Adhikari, Bipin, Promnarate, Cholrawee, Chotivanich, Kesinee, Hanboonkunupakarn, Borimas, Jittmala, Podjanee, Cheah, Phaik Yeong, Dhorda, Mehul, Imwong, Mallika, Mukaka, Mavuto, Peerawaranun, Pimnara, Pukrittayakamee, Sasithon, Newton, Paul N., Thwaites, Guy E., Day, Nicholas P. J., Mayxay, Mayfong, Hien, Tran Tinh, Nosten, Francois H., Cobelens, Frank, Dondorp, Arjen M., White, Nicholas J., von Seidlein, Lorenz
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001954/
https://ncbi.nlm.nih.gov/pubmed/32023293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228190
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