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More than Fishing for a Cure: The Promises and Pitfalls of High Throughput Cancer Cell Line Screens

High-throughput screens in cancer cell lines (CCLs) have been used for decades to help researchers identify compounds with the potential to improve the treatment of cancer and, more recently, to identify genomic susceptibilities in cancer via genome-wide shRNA and CRISPR/Cas9 screens. Additionally,...

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Detalhes bibliográficos
Publicado no:Pharmacol Ther
Main Authors: Ling, Alexander, Gruener, Robert F., Fessler, Jessica, Huang, R. Stephanie
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001883/
https://ncbi.nlm.nih.gov/pubmed/29953899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2018.06.014
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