Mitochondrial transfer from MSCs to T cells induces Treg differentiation and restricts inflammatory response

Mesenchymal stem cells (MSCs) have fueled ample translation for the treatment of immune‐mediated diseases. They exert immunoregulatory and tissue‐restoring effects. MSC‐mediated transfer of mitochondria (MitoT) has been demonstrated to rescue target organs from tissue damage, yet the mechanism remai...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO Rep
Prif Awduron: Court, Angela C, Le‐Gatt, Alice, Luz‐Crawford, Patricia, Parra, Eliseo, Aliaga‐Tobar, Victor, Bátiz, Luis Federico, Contreras, Rafael A, Ortúzar, María Ignacia, Kurte, Mónica, Elizondo‐Vega, Roberto, Maracaja‐Coutinho, Vinicius, Pino‐Lagos, Karina, Figueroa, Fernando E, Khoury, Maroun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001501/
https://ncbi.nlm.nih.gov/pubmed/31984629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948052
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