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Electron tomography reveals aspects of spindle structure important for mechanical stability at metaphase

Metaphase spindles exert pole-directed forces on still-connected sister kinetochores. The spindle must counter these forces with extensive forces to prevent spindle collapse. In small spindles, kinetochore microtubules (KMTs) connect directly with the poles, and countering forces are supplied either...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: O’Toole, Eileen, Morphew, Mary, McIntosh, J. Richard
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001478/
https://ncbi.nlm.nih.gov/pubmed/31825721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-07-0405
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