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miR24-2 Promotes Malignant Progression of Human Liver Cancer Stem Cells by Enhancing Tyrosine Kinase Src Epigenetically

MicroRNA24-2 (miR24-2) is associated with human tumorigenesis; however, its molecular mechanisms are poorly understood. Herein, our findings demonstrate that miR24-2 promotes the proliferation ability in vitro and the tumorigenic ability in vivo in human liver cancer stem cells (hLCSCs). Mechanicall...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Wang, Liyan, Li, Xiaonan, Zhang, Wei, Yang, Yuxin, Meng, Qiuyu, Wang, Chen, Xin, Xiaoru, Jiang, Xiaoxue, Song, Shuting, Lu, Yanan, Pu, Hu, Gui, Xin, Li, Tianming, Xu, Jie, Li, Jiao, Jia, Song, Lu, Dongdong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001004/
https://ncbi.nlm.nih.gov/pubmed/31732298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.10.015
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