Altered platelet proteome in lupus anticoagulant (LA)-positive patients—protein disulfide isomerase and NETosis as new players in LA-related thrombosis

Patients with antiphospholipid syndrome (APS) are at high risk of developing venous and arterial thromboembolism (TE). The role of platelets in the pathogenesis of these prothrombotic conditions is not yet fully understood. The aim of this study was to gain mechanistic insights into the role of plat...

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Publicat a:Exp Mol Med
Autors principals: Hell, Lena, Lurger, Kristina, Mauracher, Lisa-Marie, Grilz, Ella, Reumiller, Christina Maria, Schmidt, Georg Johannes, Ercan, Huriye, Koder, Silvia, Assinger, Alice, Basilio, José, Gebhart, Johanna, Ay, Cihan, Pabinger, Ingrid, Zellner, Maria
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000701/
https://ncbi.nlm.nih.gov/pubmed/31956273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0358-4
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