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Distinct editing functions of natural HLA-DM allotypes impact antigen presentation and CD4(+) T cell activation
Classical human leukocyte antigen (HLA) molecules of the major histocompatibility class II (MHCII) complex present peptides for the development, surveillance and activation of CD4(+) T cells. The nonclassical MHCII-like protein HLA-DM (DM) catalyzes the exchange and loading of peptides onto MHCII mo...
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| Publicado no: | Cell Mol Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7000412/ https://ncbi.nlm.nih.gov/pubmed/30467419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-018-0181-1 |
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