Dysregulation of the splicing machinery is directly associated to aggressiveness of prostate cancer

BACKGROUND: Dysregulation of splicing variants (SVs) expression has recently emerged as a novel cancer hallmark. Although the generation of aberrant SVs (e.g. AR-v7/sst5TMD4/etc.) is associated to prostate-cancer (PCa) aggressiveness and/or castration-resistant PCa (CRPC) development, whether the mo...

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Veröffentlicht in:EBioMedicine
Hauptverfasser: Jiménez-Vacas, Juan M., Herrero-Aguayo, Vicente, Montero-Hidalgo, Antonio J., Gómez-Gómez, Enrique, Fuentes-Fayos, Antonio C., León-González, Antonio J., Sáez-Martínez, Prudencio, Alors-Pérez, Emilia, Pedraza-Arévalo, Sergio, González-Serrano, Teresa, Reyes, Oscar, Martínez-López, Ana, Sánchez-Sánchez, Rafael, Ventura, Sebastián, Yubero-Serrano, Elena M., Requena-Tapia, María J., Castaño, Justo P., Gahete, Manuel D., Luque, Raúl M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Research paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000340/
https://ncbi.nlm.nih.gov/pubmed/31902674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.11.008
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