Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart

While the heart regenerates poorly in mammals, efficient heart regeneration occurs in zebrafish. Studies in zebrafish have resulted in a model in which preexisting cardiomyocytes dedifferentiate and reinitiate proliferation to replace the lost myocardium. To identify which processes occur in prolife...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Honkoop, Hessel, de Bakker, Dennis EM, Aharonov, Alla, Kruse, Fabian, Shakked, Avraham, Nguyen, Phong D, de Heus, Cecilia, Garric, Laurence, Muraro, Mauro J, Shoffner, Adam, Tessadori, Federico, Peterson, Joshua Craiger, Noort, Wendy, Bertozzi, Alberto, Weidinger, Gilbert, Posthuma, George, Grün, Dominic, van der Laarse, Willem J, Klumperman, Judith, Jaspers, Richard T, Poss, Kenneth D, van Oudenaarden, Alexander, Tzahor, Eldad, Bakkers, Jeroen
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2019
主題:
Developmental Biology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000220/
https://ncbi.nlm.nih.gov/pubmed/31868166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50163
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