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Muscle stem cell renewal suppressed by Gas1 can be reversed by GDNF in mice

Muscle undergoes progressive weakening and regenerative dysfunction with age due in part to the functional decline of skeletal muscle stem cells (MuSCs). MuSCs are heterogeneous but whether their gene expression changes with age and the implication of such changes are unclear. Here we show that in m...

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Detalhes bibliográficos
Publicado no:Nat Metab
Main Authors: Li, Liangji, Rozo, Michelle, Yue, Sibiao, Zheng, Xiaobin, Tan, Frederick, Lepper, Christoph, Fan, Chen-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000153/
https://ncbi.nlm.nih.gov/pubmed/32021964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-019-0110-3
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