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Flow cytometry-based assessment of direct-targeting anti-cancer antibody immune effector functions

Monoclonal antibody-based therapies are increasingly being used to treat cancer. Some mediate their therapeutic effects through modifying the function of immune cells globally, while others bind directly to tumor cells and can recruit immune effector cells through their Fc regions. As new direct-bin...

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Библиографические подробности
Опубликовано в: :Methods Enzymol
Главные авторы: Miller, Michelle L., Finn, Olivera J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000137/
https://ncbi.nlm.nih.gov/pubmed/32000909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.07.026
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