Interaction Proteomics Identifies ERbeta Association with Chromatin Repressive Complexes to Inhibit Cholesterol Biosynthesis and Exert An Oncosuppressive Role in Triple-negative Breast Cancer

Triple-negative breast cancer (TNBC) is characterized by poor response to therapy and low overall patient survival. Recently, Estrogen Receptor beta (ERβ) has been found to be expressed in a fraction of TNBCs where, because of its oncosuppressive actions on the genome, it represents a potential ther...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Proteomics
Prif Awduron: Alexandrova, Elena, Giurato, Giorgio, Saggese, Pasquale, Pecoraro, Giovanni, Lamberti, Jessica, Ravo, Maria, Rizzo, Francesca, Rocco, Domenico, Tarallo, Roberta, Nyman, Tuula A., Collina, Francesca, Cantile, Monica, Di Bonito, Maurizio, Botti, Gerardo, Nassa, Giovanni, Weisz, Alessandro
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Biochemistry and Molecular Biology 2020
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000115/
https://ncbi.nlm.nih.gov/pubmed/31792072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001817
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