Dorsal amygdala neurotrophin-3 decreases anxious temperament in primates

BACKGROUND: An early-life anxious temperament (AT) is a risk factor for the development of anxiety, depression, and comorbid substance abuse. We validated a nonhuman primate (NHP) model of early-life AT and identified the dorsal amygdala as a core component of AT’s neural circuit. Here, we combine R...

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Gepubliceerd in:Biol Psychiatry
Hoofdauteurs: Fox, Andrew S., Souaiaia, Tade, Oler, Jonathan A, Kovner, Rothem, Kim, Jae Mun (Hugo), Nguyen, Joseph, French, Delores A, Riedel, Marissa, Fekete, Eva, Rabska, Matthew R, Olsen, Miles E, Brodsky, Ethan K, Alexander, Andrew L., Block, Walter F., Roseboom, Patrick H, Knowles, James A, Kalin, Ned H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6999854/
https://ncbi.nlm.nih.gov/pubmed/31422797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2019.06.022
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