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Comparative Study of Protective Effect of Cimetidine and Verapamil on Paracetamol-Induced Hepatotoxicity in Mice

Paracetamol, chemically known as acetaminophen, if taken in higher doses has hepatotoxic potential. Cimetidine by inhibiting the cytochromal enzymes and reducing the production of the toxic metabolite can reduce the hepatotoxic potential while Verapamil can act as a hepatoprotective by maintaining c...

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Detalhes bibliográficos
Publicado no:Int J Hepatol
Main Authors: Danish, Lubna, Siddiq, Riffat, Jahan, Sarwat, Taneez, Mehwish, Khan, Manzoor, Sandhu, Marva
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6998752/
https://ncbi.nlm.nih.gov/pubmed/32099681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/9185361
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