Dysregulation of TNF-α and IFN-γ expression is a common host immune response in a chronically infected mouse model of melioidosis when comparing multiple human strains of Burkholderia pseudomallei

BACKGROUND: Melioidosis is endemic in Southeast Asia and Northern Australia and is caused by the Gram-negative, facultative intracellular pathogen Burkholderia pseudomallei. Diagnosis of melioidosis is often difficult because of the protean clinical presentation of the disease, and it may mimic othe...

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Veröffentlicht in:BMC Immunol
Hauptverfasser: Amemiya, Kei, Dankmeyer, Jennifer L., Bearss, Jeremy J., Zeng, Xiankun, Stonier, Spencer W., Soffler, Carl, Cote, Christopher K., Welkos, Susan L., Fetterer, David P., Chance, Taylor B., Trevino, Sylvia R., Worsham, Patricia L., Waag, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6998218/
https://ncbi.nlm.nih.gov/pubmed/32013893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-020-0333-9
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