PLOD2 Is Essential to Functional Activation of Integrin β1 for Invasion/Metastasis in Head and Neck Squamous Cell Carcinomas

Identifying the specific functional regulator of integrin family molecules in cancer cells is critical because they are directly involved in tumor invasion and metastasis. Here we report high expression of PLOD2 in oropharyngeal squamous cell carcinomas (SCCs) and its critical role as a stabilizer o...

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Udgivet i:iScience
Main Authors: Ueki, Yushi, Saito, Ken, Iioka, Hidekazu, Sakamoto, Izumi, Kanda, Yasuhiro, Sakaguchi, Masakiyo, Horii, Arata, Kondo, Eisaku
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997870/
https://ncbi.nlm.nih.gov/pubmed/32058962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100850
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