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Adult hypophosphatasia with a novel ALPL mutation: Report of an Indian kindred

Hypophosphatasia is an inborn error in metabolism characterized by low serum alkaline phosphatase (ALP) activity resulting from deactivating mutations in TNSALP (also known as ALPL), the gene that encodes the ‘tissue-specific’ isoenzyme of ALP. The disease exhibits significant clinical heterogeneity...

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Détails bibliographiques
Publié dans:Bone Rep
Auteurs principaux: Bhadada, Sanjay K., Pal, Rimesh, Dhiman, Vandana, Alonso, Nerea, Ralston, Stuart H., Kaur, Simran, Gupta, Rajat
Format: Artigo
Langue:Inglês
Publié: Elsevier 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997823/
https://ncbi.nlm.nih.gov/pubmed/32025537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bonr.2020.100247
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