HIV-1 Accessory Protein Vpr Interacts with REAF/RPRD2 To Mitigate Its Antiviral Activity

The human immunodeficiency virus type 1 (HIV-1) accessory protein Vpr enhances viral replication in both macrophages and, to a lesser extent, cycling T cells. Virion-packaged Vpr is released in target cells shortly after entry, suggesting it is required in the early phase of infection. Previously, w...

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Veröffentlicht in:J Virol
Hauptverfasser: Gibbons, Joseph M., Marno, Kelly M., Pike, Rebecca, Lee, Wing-yiu Jason, Jones, Christopher E., Ogunkolade, Babatunji W., Pardieu, Claire, Bryan, Alexander, Fu, Rebecca Menhua, Warnes, Gary, Rowley, Paul A., Sloan, Richard D., McKnight, Áine
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997760/
https://ncbi.nlm.nih.gov/pubmed/31776272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01591-19
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