Two Pioneer Transcription Factors, Krüppel-Like Transcription Factor 4 and Glucocorticoid Receptor, Cooperatively Transactivate the Bovine Herpesvirus 1 ICP0 Early Promoter and Stimulate Productive Infection

An important site for bovine herpesvirus 1 (BoHV-1) latency is sensory neurons within trigeminal ganglia (TG). The synthetic corticosteroid dexamethasone consistently induces BoHV-1 reactivation from latency. Expression of four Krüppel-like transcription factors (KLF), i.e., KLF4, KLF6, PLZF (promye...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: El-mayet, Fouad S., Sawant, Laximan, Thunuguntla, Prasanth, Zhao, Jing, Jones, Clinton
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997752/
https://ncbi.nlm.nih.gov/pubmed/31776270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01670-19
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