Human Papillomavirus E7 Oncoprotein Subverts Host Innate Immunity via SUV39H1-Mediated Epigenetic Silencing of Immune Sensor Genes

Subversion of innate immunity by oncoviruses, such as human papillomavirus (HPV), favors carcinogenesis because the mechanism(s) of viral immune evasion can also hamper cancer immunosurveillance. Previously, we demonstrated that high-risk (hr) HPVs trigger simultaneous epigenetic silencing of multip...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Lo Cigno, Irene, Calati, Federica, Borgogna, Cinzia, Zevini, Alessandra, Albertini, Silvia, Martuscelli, Licia, De Andrea, Marco, Hiscott, John, Landolfo, Santo, Gariglio, Marisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997746/
https://ncbi.nlm.nih.gov/pubmed/31776268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01812-19
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