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Up-regulated FHL2 inhibits ovulation through interacting with androgen receptor and ERK1/2 in polycystic ovary syndrome

BACKGROUND: The ovulatory dysfunction mechanisms underlying polycystic ovary syndrome (PCOS) are not completely understood. There is no effective therapy for PCOS so far. METHODS: We measured the expression of four and a half LIM domain 2 (FHL2) and other related-genes in human granulosa cells (hGCs...

詳細記述

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書誌詳細
出版年:EBioMedicine
主要な著者: Zhou, Ruiqiong, Li, Shang, Liu, Jiansheng, Wu, Hasiximuke, Yao, Guangxin, Sun, Yun, Chen, Zi-Jiang, Li, Weiping, Du, Yanzhi
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997507/
https://ncbi.nlm.nih.gov/pubmed/32028069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102635
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