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A Combined Systematic-Stochastic Algorithm for the Conformational Search in Flexible Acyclic Molecules

We propose an algorithm that is a combination of systematic variation of the torsions and Monte Carlo (or stochastic) search. It starts with a trial geometry in internal coordinates and with a set of preconditioned torsional angles, i.e., torsional angles at which minima are expected according to th...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Ferro-Costas, David, Fernández-Ramos, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997476/
https://ncbi.nlm.nih.gov/pubmed/32047738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00016
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